Alcohol drinking status by age and sex. Alcohol Use Statistics.



Alcohol drinking status by age and sex

Alcohol drinking status by age and sex

Advanced Search Abstract Aims: While serum gamma-glutamyltransferase GGT enzyme activity is a well established biomarker of excessive alcohol consumption and liver dysfunction, recent studies have also implicated it as a predictor of morbidity due to extrahepatic causes. Therefore, further information on the associations between ethanol intake and GGT activities in apparently healthy individuals appears warranted. Data on alcohol consumption and serum GGT activities were collected from 18, individuals men, 10, women , mean age 48 years and range 25—74 years, who participated in a national cross-sectional health survey.

Alcohol use was assessed by detailed questionnaires and the study population was subsequently divided into subgroups according to age and gender. Body mass index and smoking were used as covariates in all analyses. For women, the corresponding threshold levels were four and seven standard ethanol doses, respectively.

The data pertaining to the present population sample indicate that rather low levels of reported regular ethanol consumption lead to elevated levels of GGT and that age over 40 markedly enhances the impact of alcohol consumption on GGT activity. The present findings should form the basis for defining safe levels of ethanol consumption and in recalibrating goals for normal limits in the clinical use of GGT measurements.

It plays a pivotal role in the extracellular metabolism of glutathione and thereby regulates oxidant stress status in vivo Lee et al. Consequently, there has been growing interest in the significance of alterations in serum GGT levels as a general indicator of health and disease. A trend towards increased mean GGT activities at population level has been observed in several recent surveys, which has been linked with increased alcohol consumption and prevalence of obesity in populations Sillanaukee et al.

It has been further hypothesized that changes in serum GGT could be considered a marker of oxidative stress Lee et al. Although heavy alcohol drinking is known to elevate the levels of serum GGT, studies of GGT response to mild or moderate ethanol intake in large populations have, however, been limited.

This work investigates the association between GGT and alcohol consumption in a large age- and gender-stratified population of apparently healthy individuals with different levels of alcohol consumption. In each year, an age- and a gender-stratified random sample was drawn from the population register according to an international WHO MONICA Monitoring trends and determinants in cardiovascular disease project protocol. The survey included a detailed questionnaire on health status and alcohol intake, physical measurements and laboratory tests.

The questionnaire covered information on current health behaviour, health status, medical history and socioeconomic factors. The medical examinations were conducted using a previously described standardized protocol The World Health Organization, All the surveys were conducted in accordance with the Declaration of Helsinki according to the ethical rules of the National Public Health Institute.

The present sample included data from the subjects who both filled out the questionnaire and attended the medical examination. The final population thus comprised 18, individuals: Smoking was quantified as the amount of cigarettes per day. Alcohol consumption was assessed with detailed questions on the type of alcoholic beverage consumed, the frequency of consumption and the amount of ethanol-containing drinks consumed regularly during the past weeks and 1 year prior to sampling.

The amount of ethanol in different beverages was quantified as follows: The subjects were subsequently classified into groups as follows: The population was also divided into two age groups: The main characteristics of the study population classified into subgroups according to alcohol consumption.

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Alcohol drinking status by age and sex

Advanced Search Abstract Aims: While serum gamma-glutamyltransferase GGT enzyme activity is a well established biomarker of excessive alcohol consumption and liver dysfunction, recent studies have also implicated it as a predictor of morbidity due to extrahepatic causes.

Therefore, further information on the associations between ethanol intake and GGT activities in apparently healthy individuals appears warranted. Data on alcohol consumption and serum GGT activities were collected from 18, individuals men, 10, women , mean age 48 years and range 25—74 years, who participated in a national cross-sectional health survey.

Alcohol use was assessed by detailed questionnaires and the study population was subsequently divided into subgroups according to age and gender. Body mass index and smoking were used as covariates in all analyses.

For women, the corresponding threshold levels were four and seven standard ethanol doses, respectively. The data pertaining to the present population sample indicate that rather low levels of reported regular ethanol consumption lead to elevated levels of GGT and that age over 40 markedly enhances the impact of alcohol consumption on GGT activity. The present findings should form the basis for defining safe levels of ethanol consumption and in recalibrating goals for normal limits in the clinical use of GGT measurements.

It plays a pivotal role in the extracellular metabolism of glutathione and thereby regulates oxidant stress status in vivo Lee et al. Consequently, there has been growing interest in the significance of alterations in serum GGT levels as a general indicator of health and disease. A trend towards increased mean GGT activities at population level has been observed in several recent surveys, which has been linked with increased alcohol consumption and prevalence of obesity in populations Sillanaukee et al.

It has been further hypothesized that changes in serum GGT could be considered a marker of oxidative stress Lee et al. Although heavy alcohol drinking is known to elevate the levels of serum GGT, studies of GGT response to mild or moderate ethanol intake in large populations have, however, been limited. This work investigates the association between GGT and alcohol consumption in a large age- and gender-stratified population of apparently healthy individuals with different levels of alcohol consumption.

In each year, an age- and a gender-stratified random sample was drawn from the population register according to an international WHO MONICA Monitoring trends and determinants in cardiovascular disease project protocol. The survey included a detailed questionnaire on health status and alcohol intake, physical measurements and laboratory tests. The questionnaire covered information on current health behaviour, health status, medical history and socioeconomic factors.

The medical examinations were conducted using a previously described standardized protocol The World Health Organization, All the surveys were conducted in accordance with the Declaration of Helsinki according to the ethical rules of the National Public Health Institute.

The present sample included data from the subjects who both filled out the questionnaire and attended the medical examination. The final population thus comprised 18, individuals: Smoking was quantified as the amount of cigarettes per day.

Alcohol consumption was assessed with detailed questions on the type of alcoholic beverage consumed, the frequency of consumption and the amount of ethanol-containing drinks consumed regularly during the past weeks and 1 year prior to sampling. The amount of ethanol in different beverages was quantified as follows: The subjects were subsequently classified into groups as follows: The population was also divided into two age groups: The main characteristics of the study population classified into subgroups according to alcohol consumption.

Alcohol drinking status by age and sex

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